Cannabis Flavonoids – Emerging Therapeutic Applications
DR. TITUS INSIGHTS: NSAIDS, FLAVONOIDS, AND AUTISM
Flavonoids are a group of phytonutrients most remarkably known for providing vivid non-green pigments to the plant kingdom, such as the blue in blueberries, the red in red roses and the purple in your Granddaddy Purp Cannabis. Alongside cannabinoids (such as THC and CBD) and terpenoids (such as myrcene and limonene), flavonoids in cannabis also produce a range of effects. Commonly grouped together, flavonoids combine together to supplement the other cannabis phytonutrients – and play a highly bioactive role in the plant’s consumption and cultivation.
When cannabis is consumed, flavonoids contribute to the color, taste, smell, entourage effect and overall sensory experience. While contributing to health benefits of the cannabis plant, these flavonoids also have a great reputation among the wellness community for providing a range of health benefits to humans.
Federal prohibition has prevented more study and research in regards to cannabis related flavonoids; however, this class represents one of the largest nutrient families known to science. Over 6,000 individual flavonoids have been identified and many are found in the fruits, vegetables and herbs that we routinely consume.
A type of flavonoid found in green tea and cacao known as “catechins” is known to provide antioxidant and cardiovascular health benefits, while also providing favorable effects upon cholesterol levels in humans. Another flavonoid, known as “quercetin” which is readily available in many fruits and vegetables (as well as in cannabis) is known for having potential antioxidant and anti-viral properties.
Certain flavonoids are unique to the cannabis plant and are now referred to as “cannaflavins” and research is underway to distinguish cannaflavins from more common flavonoids. Recently it was discovered that a cannaflavin known as “Cannaflavin-A” inhibits PGE-2, a prostaglandin responsible for inflammation – similar to the effect of NSAIDs like aspirin. The research study showed that “Cannaflavin-A” reduces inflammation and is exponentially more powerful than aspirin.
Cannaflavin-B and Cannaflavin-C are being studied as well. Researchers continue their work on more common flavonoids in plants that also appear in cannabis: such as beta-sitosterol, vitexin, isovitexin, apigenin, kaempferol, quercetin, luteolin and orientin – whether these flavonoids enhance or reduce certain effects of cannabis based cannabinoids and/or terpenoids.
Because of the high level of anti-inflammatory properties that support detoxification of tissue-damaging molecules, flavonoids consumption if often associated with reduced risk of certain cancers, most notably lung and breast cancer. Flavonoids are readily found on the cured leaves and flowers of cannabis and through advanced extraction techniques, we may soon be combining cannabinoids with a ribbon of “flav” oil.
Here is a list of some major flavonoids, potential therapeutic effects and their corresponding vaporization temperatures:
Beta-sitosterol: 273 degrees F; anti-inflammatory
Apigenin; 352 degrees F; estrogenic, anxiolytic, anti-inflammatory
Cannaflavin-A; 360 degrees F; anti-inflammatory
Quercetin; 482 degrees F; antioxidant, antiviral
More info: https://www.merryjane.com/health/flavonoids-cannabis