Other Compounds and Chemicals Found in Cannabinoids


The Compounds and Chemicals in Cannabinoids

Over the past decade, medical research has made intriguing discoveries about cannabis and its chemical makeup. While there’s still so much to learn about cannabis’ natural constituents, scientists have so far identified 483 different chemical compounds in cannabis22. In addition to containing over 85 cannabinoids, cannabis is a great source of terpenes, flavonoids, chlorophyll, vitamins, minerals, and omega fatty acids.

Studies indicate that the cannabinoids, terepenes, vitamins, and other natural constituents work with the body naturally and synergistically to produce therapeutic effects in what’s become known as the entourage effect17,23.

Interested in learning more about cannabinoids? Please visit our page explaining the major and minor cannabinoids found in cannabis.

Below you can learn more about the other compounds in cannabis, including:

Fatty Acids and Vitamins

That distinct smell of cannabis comes from terpenes, fragrant essential oils that are found in highest concentrations within cannabis flowers, or buds. Terpenes are not unique to cannabis and are found in other plants, fruits, pine trees, and herbs, however so far over 100 different possible terpenes have been identified in the cannabis plant.

The type of terpenes a particular cannabis strain contains will influence its smell and flavor. Each has a unique aroma. The benefits of terpenes go beyond making cannabis taste or smell a different way, however, Research shows that terpenes bind to receptors and neurotransmitters in the brain to elicit various reactions, interacting synergistically with the other cannabis compounds21.

Some terpenes – including myrcene, cintronellol, and linalool – are beneficial for their sedation, relaxation, and calming effects. Others — like limonene and pinene – boost alertness and elevate mood. Other more widely recognizable terpenes that are still being scientifically explored include caryophyllene, bisabolol, and humulene.

Compared to cannabinoids, not much is known about the therapeutic effects of terpenes. However, research indicates that terpenes do possess several beneficial properties, including antiseptic, anti-bacterial, anti-cancer, antioxidant, antifungal, antiseptic, pain-relieving, anti-inflammatory, anti-anxiety and anti-spastic effects3,4,9,13,14,15,16,19,20,21,24,28,29.


Flavonoids are a group of phytonutrients that are responsible for providing the non-green pigments to plant life, and for contributing to the taste and smell of fruits, vegetables, and herbs. Like cannabinoids and terpenes, flavonoids have been shown to offer a range of therapeutic effects.

While flavonoids are found in many of the edible plants that we’re familiar with, like tomatoes and blueberries, researchers believe that cannabis is also a flavonoid-rich resource and that they’re primarily found on cannabis’ cured leaves and flowers.

Flavonoids are among the largest nutrient families known to science, and researchers have so far identified over 6,000 ones that are unique. Flavonoids are famous for their antioxidant and anti-inflammatory health benefits and have been associated with a reduced risk of a variety of diseases, such as multiple sclerosis, rheumatoid arthritis, and edema10,11,12,17,18.

Federal laws have prevented researchers from thoroughly exploring the flavonoids that are unique to cannabis, referred to as cannaflavins. However, the research that has been done indicates that cannaflavins are as beneficial as the flavonoids found in the more traditional fruits and vegetables we eat.

The flavonoid cannaflavin-A, for example, has been shown to possess anti-inflammatory effects. One study found that it inhibited PG-2, a prostaglandin responsible for inflammation, and proved to be more effective than aspirin2.


Depending on how you consume medical cannabis, it could contain chlorophyll, the chemical substance that gives all plants, like cannabis, their green pigment. When cannabis is harvested, it’s full of chlorophyll. Cannabis flower goes through a drying process, which converts the chlorophyll into glucose and in turn improves its flavor.

Pressed cannabis oil, however, still contain chlorophyll, which has been shown to possess several beneficial properties, including being an antioxidant and anti-inflammatory agent8,26,31. In studies, chlorophyll has shown to help suppress hunger and stabilize blood sugar levels, suggesting it could be beneficial in the treatment of obesity and diabetes25. Chlorophyll has also shown to be beneficial in the healing of wounds30. Multiple studies suggest that chlorophyll has anti-cancer properties1,5,7,8.

Fatty Acids and Vitamins

An imbalance of fatty acids promotes inflammation and encourages diseases, but raw cannabis contains the optimal 3:1 ratio of Omega-3 to Omega-6 fatty acids to provide several therapeutic benefits. Omega-3 and Omega-6 fatty acids possess anti-inflammatory and protective properties to help lower the risk of heart disease and reduce the risk of type 2 diabetes,

Alzheimer’s disease and age-related brain decline27. Omega-3 and Omega-6 fatty acids are also essential in the process of producing endocannabinoids and cannabinoid receptors. The body doesn’t naturally synthesize Omega-3 and Omega-6 fatty acids, so you have to get them from foods and substances, like cannabis, that you consume.

Cannabis oil extracted from Cannabis is also rich in an extensive list of vitamins, giving users the nutrients they need to improve and maintain health. Cannabis naturally contains vitamins A, C, and E, as well as B complex vitamins like riboflavin, thiamine, and niacin. Cannabis also contains vitamins that are not typically not found in most people’s diets, like beta carotene. Cannabis oil is also an adequate source of several minerals, including zinc, potassium, calcium, phosphorous, iron, and magnesium.


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